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HLA-B27 Test: Costs, Purpose, Normal Range and Interpretation

HLA-B27 Test (Human Leukocyte Antigen B27)
  • Sample Type : Blood
  • Parameters : 1
  • Report Time : 24/48 Hrs
  • Home Collection: Yes
  • Fasting : Not Required
  • Age Group: All
OFFER PRICE:  ₹1908 ₹2700 30% off


Hla-b27 Test
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The HLA-B27 (Human Leukocyte Antigen) Test detects the presence of the HLA-B27 (or human leukocyte antigen B27 antigen), a protein present on the surface of white blood cells. This test forecasts the likelihood of acquiring autoimmune disorders such ankylosing spondylitis and reactive arthritis. It is important to note, however, that not all people who test positive for HLA-B27 suffer these illnesses. These disorders and their symptoms can affect anyone, including people who lack HLA-B27.

Do you know how to get the HLA-B27 blood Testdone? Read more to find out how you can prepare for it.

Why Do I Need HLA-B27 Blood Test?

The HLA-B27 Test reveals whether you are genetically predisposed to certain autoimmune disorders such as ankylosing spondylitis and certain types of arthritis. To assist doctors in diagnosing these problems and developing a treatment plan, this test will help.

How To Prepare For HLA-B27 Testing?

You should do the below mentioned things to prepare for the HLA-B27 blood test:

  • Discuss any drugs you are consuming with your doctor and whether you need to stop taking them before the test.
  • Fast for at least 8 hours before undertaking the test, as directed by your doctor.
  • Drink plenty of water before the test to make obtaining a blood sample easier.
  • Wear a short-sleeved shirt or blouse to make it easier for the healthcare provider to access a vein in your arm.
  • It's important to follow your doctor's instructions and ask any questions you have about the test. The HLA-B27 Test is usually straightforward, but preparation can help it go smoothly.

What Happens During HLA-B27 Testing?

The HLA-B27 Test does not require any extra preparation. It is a basic blood test that involves collecting blood from a vein in your arm. The lab will use a variety of techniques to identify the presence of HLA-B27 protein in the blood. A positive result does not necessarily mean the patient has the autoimmune disorder, but indicates a higher risk. Further medical evaluation and diagnostic tests may be required to confirm a diagnosis and determine the best course of treatment.

Should you order an HLA-B27 test at home or go to your local clinic? Read on to find out what works best for you.

Can I Take HLA-B27 Test At Home?

No, the HLA-B27 blood test is typically not available for home use. It requires a blood sample, usually collected at a doctor's office or a laboratory, and sent to the lab for further analysis. If you need an HLA-B27 Test, you must speak with your doctor and make an appointment to have the test done.

How Much Does HLA-B27 Test Cost?

The regular HLA-B27 Test price depends on the diagnostic center you choose to get it done. In most cases, your insurance is enough to cover the cost of the HLA-B27 Test, but if it isn’t, you can always purchase a new plan at affordable rates.

You undertook the HLA-B27 and got your results, but you still need help determining if you have antibodies in the normal range. Read this section to understand how to go about your cancer diagnosis with your healthcare professional.

What Do HLA-B27 Test Results Mean?

If you have HLA-B27 positive results, it indicates the presence of the antigen, and it suggests an increased risk of developing these conditions. However, a positive test does not necessarily mean that an individual will experience the conditions, as many people with the antigen never develop symptoms. On the contrary, HLA-B27 negative result indicates that the antigen isn't present and suggests a lower risk of developing the conditions.

It's important to note that HLA-B27 is just one of several genetic and environmental factors that contribute to the development of autoimmune disorders and that a positive test result should not be considered a diagnosis.

What Is HLA-B27 Test Normal Range?

The normal range for the HLA-B27 blood test is negative or not present.

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Ref Links:

  1. HLA-B27 antigen Information - Blood test - Mount Sinai
  2. HLA-B27 Antigen - Health Encyclopedia - URMC
  3. Human Leukocyte Antigen B27 (HLA-B27) - Healthline
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FAQs Around HLA-B27 Test (Human Leukocyte Antigen)

The presence of HLA-B27 can weaken your immune system, which might start attacking your healthy cells. This phenomenon can result in an autoimmune or immune-mediated disease, such as juvenile rheumatoid arthritis or ankylosing spondylitis.

HLA-B27 is a genetic marker found on certain human leukocyte antigen (HLA) molecules involved in the immune system. A positive test result for HLA-B27 means that the person has this genetic marker.

No, HLA-B27 positive is not a curable condition. HLA-B27 is a genetic marker associated with increased susceptibility to certain autoimmune and inflammatory diseases, such as Ankylosing Spondylitis and Inflammatory Bowel Disease, which get managed with medical treatments, lifestyle changes, etc.

A positive HLA-B27 suggests an increased risk of developing certain autoimmune diseases such as Ankylosing Spondylitis, Inflammatory Bowel Disease, Psoriatic Arthritis, and Reactive Arthritis. However, experts also state that a positive result doesn't guarantee that you will develop one of these conditions.

HLA-B27 negative does not exist. You either have it, or you don't.

The HLA-B27 Test determines if an individual has a specific genetic marker associated with an increased risk of developing certain autoimmune diseases, like ankylosing spondylitis, & others. This test can help medical experts make a diagnosis, predict disease progression, & plan a treatment strategy.

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  • Disclaimer: HealthcareOnTime offers extensively researched information, including laboratory testing for health screening. However, we must emphasize that this content is not intended as a substitute for professional medical advice or diagnosis. Always prioritize consulting your healthcare provider for accurate medical guidance and personalized treatment. Remember, your health is of paramount importance, and only a qualified medical professional can make precise determinations regarding your well-being. Protection Status Protection Status Protection Status