The HLA-B27 Test (Human Leukocyte Antigen Test) is a blood test used to determine the presence of the HLA-B27 (or human leukocyte antigen B27 antigen), a protein found on the surface of white blood cells. This test predicts the risk of developing certain autoimmune diseases, such as ankylosing spondylitis and reactive arthritis. However, it's worth remembering that not all individuals who test positive for HLA-B27 develop these conditions. These diseases and their symptoms can be present in anyone, including those who do not have HLA-B27.
About the HLA-B27 Test
The HLA-B27 blood test determines the presence of the human leukocyte antigen (HLA) B27 gene, a genetic marker associated with increased risk for certain autoimmune diseases, such as ankylosing spondylitis, psoriatic arthritis, and inflammatory bowel disease.
However, it's important to note that the presence of the HLA-B27 antigen does not guarantee that an individual will develop these conditions. Several individuals with the HLA-B27 gene never experience any health problems.
Why do I need the HLA-B27 Test?
The HLA-B27 Test determines if you have a genetic predisposition to certain autoimmune diseases, such as ankylosing spondylitis and different types of arthritis. The test can help healthcare providers diagnose these conditions and develop a treatment plan.
What does the HLA-B27 Test measure?
The HLA-B27 Test measures the presence of the HLA-B27 gene. This human leukocyte antigen gene is associated with an increased risk of developing certain autoimmune diseases such as ankylosing spondylitis, psoriatic arthritis, reactive arthritis, and others.
How do I prepare for the HLA-B27 Test?
To prepare for the HLA-B27 blood test, you should:
Talk to your doctor about any medications you're taking and whether you need to stop taking them before the test.
Fast for at least 8 hours before undertaking the test, as directed by your doctor.
Drink plenty of water before the test to make obtaining a blood sample easier.
Wear a short-sleeved shirt or blouse to make it easier for the healthcare provider to access a vein in your arm.
It's important to follow your doctor's instructions and ask any questions you have about the test. The HLA-B27 Test is usually straightforward, but preparation can help it go smoothly.
What sample is required for the HLA-B27 Test?
The test is performed by drawing a blood sample and analyzing the genetic material within the white blood cells. Results of the Human Leukocyte Antigen Test are usually available within a few days. A doctor typically orders the test as part of an evaluation for symptoms that suggest an autoimmune disorder, such as joint pain, stiffness, or swelling.
What happens during an HLA-B27 Test?
There is no special preparation required for the HLA-B27 Test. It is a simple blood test that requires drawing a blood sample from the vein in your arm.
What are the risks involved in the HLA-B27 Test?
The risks involved in the HLA-B27 Test are minimal and mainly include the following:
Pain or discomfort from the needle puncture used to draw the blood sample
Bruising or swelling at the puncture site
Fainting or dizziness, especially in people who have a fear of needles
Infection from the needle puncture, although this is rare.
It is important to note that the test results alone do not diagnose any medical condition. It's better to interpret them in conjunction with other clinical and diagnostic information.
Finding the HLA-B27 Test
Should you call for an HLA-B27 Test at home or get it done at your nearest clinic? Read more to find out what suits your comfort.
Can I take the HLA-B27 Test at home?
No, the HLA-B27 blood test is typically not available for home use. It requires a blood sample, usually collected at a doctor's office or a laboratory, and sent to the lab for further analysis. If you need an HLA-B27 Test, you must speak with your doctor and make an appointment to have the test done.
How much does the HLA-B27 Test cost?
The regular HLA-B27 Test price depends on the diagnostic center you choose to get it done. In most cases, your insurance is enough to cover the cost of the HLA-B27 Test, but if it isn’t, you can always purchase a new plan at affordable rates.
HLA-B27 Test Results
You undertook the HLA-B27 and got your results, but you still need help determining if you have antibodies in the normal range. Read this section to understand how to go about your cancer diagnosis with your healthcare professional.
What do the HLA-B27 Test results mean?
If you have HLA-B27 positive result, it indicates the presence of the antigen, and it suggests an increased risk of developing these conditions. However, a positive test does not necessarily mean that an individual will experience the conditions, as many people with the antigen never develop symptoms. On the contrary, HLA-B27 negative result indicates that the antigen isn't present and suggests a lower risk of developing the conditions.
It's important to note that HLA-B27 is just one of several genetic and environmental factors that contribute to the development of autoimmune disorders and that a positive test result should not be considered a diagnosis.
What is an HLA-B27 Test normal range?
The normal range for the HLA-B27 blood test is negative or not present.
Why Choose HealthcareOnTime?
At HealthcareOnTime, we proudly offer a pan-India presence with well-trained experts who provide home testing services at cost-effective pricing. Our experts can conduct your HLA-B27 Test at your convenience or assist you in booking an appointment at the nearest diagnostic center.
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FAQs around HLA-B27 Test (Human Leukocyte Antigen Test)
The presence of HLA-B27 can weaken your immune system, which might start attacking your healthy cells. This phenomenon can result in an autoimmune or immune-mediated disease, such as juvenile rheumatoid arthritis or ankylosing spondylitis.
HLA-B27 is a genetic marker found on certain human leukocyte antigen (HLA) molecules involved in the immune system. A positive test result for HLA-B27 means that the person has this genetic marker.
No, HLA-B27 positive is not a curable condition. HLA-B27 is a genetic marker associated with increased susceptibility to certain autoimmune and inflammatory diseases, such as Ankylosing Spondylitis and Inflammatory Bowel Disease, which get managed with medical treatments, lifestyle changes, etc.
A positive HLA-B27 suggests an increased risk of developing certain autoimmune diseases such as Ankylosing Spondylitis, Inflammatory Bowel Disease, Psoriatic Arthritis, and Reactive Arthritis. However, experts also state that a positive result doesn't guarantee that you will develop one of these conditions.
HLA-B27 negative does not exist. You either have it, or you don???t.
The HLA-B27 Test determines if an individual has a specific genetic marker associated with an increased risk of developing certain autoimmune diseases, like ankylosing spondylitis, & others. This test can help medical experts make a diagnosis, predict disease progression, & plan a treatment strategy.
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