Lipase Test: Costs, Purpose, Normal Range and Interpretation

Lipase or Serum Lipase or S Lipase is a digestive enzyme or digestive juice that plays a crucial role in fat breakdown. This digestive enzyme is usually produced in the pancreas, stomach and salivary glands. Though a moderate level of lipase in your bloodstream is deemed normal and non-alarming, a higher level may indicate underlying health conditions, especially pertaining to the pancreas. 

A lipase test helps your healthcare provider 

• To diagnose if you have acute pancreatitis or chronic pancreatitis 
• To assess your risk of developing pancreatitis and other pancreatic disorders 
• To analyse the treatment efficacy for pancreatitis 
• To help diagnose and monitor other health conditions that impact the pancreas negatively, such as Cystic Fibrosis, Crohn Disease, Celiac Disease, etc. 

Learn everything about lipase blood test before you book your lab test online. Understand the why, how, and what of this test.

Why do I need a Serum Lipase Test? 

Your healthcare provider will recommend a serum lipase test if you 

• Are experiencing pain in your upper belly that later gets projected to your back 
• Have symptoms of nausea, vomiting and diarrhoea
• Have a swollen belly, fever and a faster heartbeat 
• Have been experiencing uncharacteristic weight loss, lack of appetite and back pain 

Your healthcare provider may also recommend the amylase along with the lipase blood test to arrive at a conclusive diagnosis for pancreatitis and other pancreatic disorders. 

How To Prepare for S Lipase Testing?

To prepare for serum Lipase Testing, follow these steps: Consult your healthcare provider, inform them about medications, avoid intense exercise, follow fasting instructions if given, and provide accurate medical history.

What Happens During Lipase Blood Testing?

S Lipase Testing only takes a few minutes. 

• As per the scheduled time of the blood test, a lab technician who usually takes blood samples will arrive.
• A thin needle will be used to draw blood from your arm’s vein.
• The needle might cause a mild pinch and some discomfort.
• The lab technician then fills a collection tube with blood and then removes the needle from the skin.
• They place a small bandage on the arm.

You've received your serum lipase test results but may be wondering if they fall within the normal range. This section will help you understand whether your lipase levels are within the typical range or not.

What Does Lipase Test Results Mean?

The serum lipase test results may vary based on the

• Gender 
• Age 
• Overall health profile 
• Method of testing 
• Laboratory 

An abnormal s lipase test result may mean underlying health conditions of the pancreas that may vary in intensity and type. 

While a higher than normal lipase level may mean acute or chronic pancreatitis, chronic disorders of the kidney, intestine, gallbladder and kidneys, a lower than lipase normal range may mean permanent pancreatic cell damage. 

What is the Serum Lipase Test Normal Range?

The lipase test normal range for people aged below 60 years is 10 - 140 U/L and 24 - 151 U/L for people aged 60 years and above. 

Anything beyond this serum lipase normal value might indicate underlying pancreatic conditions. However, to arrive at conclusive diagnosis, additional master health checkup is recommended.     

What Medical Conditions Can Cause High Lipase Levels? 

The medical conditions that can trigger high lipase test results include:

• Chronic and acute pancreatitis 
• Pancreatic cancer 
• Chronic kidney diseases 
• Kidney failure 
• Peptic ulcer 
• Gallbladder disease 
• Gallstones 
• Cholecystitis 
• Blocked intestine 
• Diabetes 
• Salivary gland disorders 
• Alcohol abuse disorders 
• Liver cirrhosis 
• Celiac disease 

What Medical Conditions Can Cause Low Lipase Levels? 

Medical conditions that may cause lower than normal lipase levels include:

• Permanent damage of pancreatic cells 
• Chronic pancreatitis
• Cystic fibrosis 

Abnormal lipase levels may be caused due to cholesterol medications and birth control pills too. So, an on-time serum lipase test is highly recommended to seek the appropriate treatment interventions. 

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Disclaimer: Although we have endeavoured to provide accurate information on this page, we strongly recommend that you seek advice from your doctor before relying on any of the test ranges or lab-test recommendations mentioned herein.