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Low creatinine levels: Causes, symptoms, and Treatments

Creatinine Test

Posted By HealthcareOnTime Team Posted on 2022-11-05
Low creatinine levels: Causes, symptoms, and Treatments

What is Creatinine? A Quick Insight

Creatinine serum is the waste product in your blood that passes through the kidneys to be filtered and eliminated from your body through urine. It’s the byproduct of a chemical compound called creatine (which helps the muscles get the energy they need).

According to medical experts, your muscle mass is directly proportional to the level of creatinine, i.e., the more muscle you have, the more creatinine serum you will produce. The level is indicative of both the muscle mass in an individual and the amount of kidney function.

When Should You Undergo the Creatinine Test?

Healthcare practitioners will always recommend you undertake the creatinine serum test to determine how well your kidneys function. The creatinine level can help them eliminate signs and symptoms of potential kidney problems.

In most cases, when your current symptoms or past medical history indicates the possibility of a kidney problem, your healthcare practitioner may recommend the test. The chances increase if: 

  • You suffer from diabetes
  • You have a family history of suffering from kidney problems
  • Your blood pressure remains high
  • You are showing symptoms of kidney disease like nausea, swollen feet & ankles, trouble sleeping, and losing appetite

The doctors may also advise you to undergo a creatinine blood test if you’re on certain oral medications which have the potential to disrupt your regular kidney functions. In such a scenario, you will frequently undertake the test allowing your healthcare expert to monitor your condition.

What to Expect Before, During, and After the Creatinine Test?

The creatinine test is a simple test categorized into two parts: Urine and Blood tests. Here’s a quick briefing on both aspects:

  • Urine Test: Your healthcare doctor will ask you to collect all urine during the 24 hours in a dedicated container. They will also help you understand how to collect and store your sample. The steps for this are:
  • Empty your bladder early in the morning and flush it away
  • For the next 24 hours, collect all your urine in the container provided
  • Ensure you’re adhering to the instructions provided by your medical expert for storing the container. In most cases, it involves keeping the container in a cool place, like a refrigerator.
  • After 24 hours, return the container to the laboratory for further analysis.
  • Blood Test: Here, the healthcare professional will collect your blood sample into a test tube or vial. They need a small amount of your blood, which they send to the laboratory for analysis. The process hardly takes 5 minutes, and after giving the sample, you’re free to continue your daily routine.

Creatinine Test Result Values & What Do They Indicate?

Medical experts state that creatinine level is lower in women than men because of less muscle mass. They also share that all individuals have different creatinine levels depending on their age, diet, and muscle mass.

Here’s the average reference range of creatinine level for both genders:

Average creatinine levels (μmol/L)

Average creatinine levels (mg/dL)

Adult Male



Adult Female



In case you’re pregnant, the average values for creatinine will vary across trimesters. Here’s a quick overview of the reference values


Mean creatinine level

Upper limit of creatinine level


56 μmol/L (0.63 mg/dL)

76 μmol/L (0.86 mg/dL)


52 μmol/L (0.59 mg/dL)

72 μmol/L (0.81 mg/dL)


54 μmol/L (0.61 mg/dL)

77 μmol/L (0.87 mg/dL)

If your creatinine level is on the higher side, it could indicate:

  • Kidney obstruction – arising due to the presence of kidney stone or enlarged prostate gland
  • Excessive consumption of protein
  • Blocked urinary tract
  • Chronic kidney disease
  • Consumption of certain oral medications, like trimethoprim, cimetidine, etc

However, if your creatinine level is on the lower side, it could be because of the following factors:

  • Malnutrition
  • Decreased muscle mass due to underlying conditions that affect your muscles and nerves
  • Liver disease –interferes with creatinine production and triggers symptoms like jaundice, swelling, abdominal pain, etc. 

Best Ways to Treat Low Levels of Creatinine?

Depending on the underlying cause of low creatinine, your healthcare expert will recommend you the treatment option that works best in your favor. Here are some of the best scenarios that arise in various situations:

  • If your creatinine value is low due to a muscular disease: In this scenario, your healthcare practitioner will treat your underlying medical condition and recommend ways to reduce muscle pain, weakness, etc. In most cases, it involves consuming corticosteroids (anti-inflammatory drugs), improving your muscle strength and quality of life.
  • If your creatinine is low during pregnancy: It requires no special treatment because, according to experts, the creatinine level normalizes after you’ve given birth to the newborn. However, if you were on any oral medication disrupting the levels, consult the doctor immediately, asking them to either minimize the dosage or give you an alternative recommendation.
  • Low creatinine level due to muscle mass: In this situation, the healthcare expert will recommend you increase your physical activity level or indulge in strength training exercises a few times a week. You can try – brisk walking, swimming, aerobics, weight lifting, etc., to strengthen yourself. However, always consult an expert before starting any new exercise regimen.
  • Low creatinine level due to malnutrition or diet: In this case, your doctor will recommend you change your diet chart. Consult a dietician or a nutritionist and include more fruits, green leafy vegetables, and protein-rich food items in your diet for effective results. 

What Makes HealthcareOnTime Your Best Choice for Creatinine Test?

HealthcareOnTime is a NABL/ISO-accredited diagnostic center that offers you a series of pathology tests at reasonable prices. For example, the creatinine test cost at HealthcareOnTime starts at as low as Rs 200/-, which is quite affordable for everyone compared to the creatinine price offered by other players in the market.

The diagnostic center, with a PAN-India presence, offers you the best medical facilities under the supervision of trained professionals. So, by consulting HealthcareOnTime experts, you can rest assured to get the best medicare possible. If visiting the center isn’t possible, you can also get tested from the comfort of your house.   

HealthcareOnTime offers you a 24*7 booking facility and constant support, which makes it easier for you to reach out to the experts anywhere, anytime.

So, take advantage of these perks and book your creatinine test with HealthcareOnTime today!

Frequently Asked Questions (FAQs)

  1. When To Worry About Creatinine Levels Being Low?

    It's generally not a cause for concern if your creatinine levels are slightly lower than usual. Still, if your levels are significantly lower than normal, it could indicate an underlying health condition that you must address.

  1. What Causes Low Creatinine?

    Your creatinine levels might be low due to kidney disease, liver disease, malnutrition, and certain medications. Working with your healthcare provider to determine the cause of low creatinine levels and the appropriate treatment is essential.

  1. What If Creatinine Is Low?

    Low creatinine levels can lead to the body's build-up of waste products. It can lead to several health concerns, including fatigue, weakness, and muscle cramps. In severe cases, low creatinine levels can lead to kidney failure, which can be life-threatening for some people.

  1. What Does Low Creatinine Mean?

    If your creatinine levels are lower than usual, it could indicate an underlying health condition affecting the kidneys' ability to filter out waste products. It includes symptoms such as kidney failure, liver disease, and malnutrition.

  1. Causes Of Low Creatinine In Adults?

    Kidney and liver disease and certain medications, including ACE and ARBs, trigger low creatinine levels in adults.

  1. How Do You Raise Low Creatinine Levels?

    To raise the creatinine levels in the body, healthcare providers recommend intaking more protein. You may also get suggested to stop taking a few medications if they reduce the creatinine level in your system.

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