Neonatal hemoglobin electrophoresis Test and its Function
The Neonatal Hemoglobin Electrophoresis Test is a specialized diagnostic tool used to identify and quantify different types of hemoglobin present in a newborn’s blood. Hemoglobin variants—such as HbA, HbF, HbS, HbC, and HbE—carry distinct electrical charges, allowing them to be separated and analyzed through electrophoresis. This test plays a critical role in early detection of hemoglobinopathies like sickle cell disease and thalassemia, enabling timely clinical intervention and long-term management. It is typically included in newborn screening panels to ensure infants with genetic blood disorders receive prompt care.
Conditions that may require Neonatal hemoglobin electrophoresis Test
This test is recommended when there is a family history of hemoglobin disorders or if a newborn presents with unexplained anemia, jaundice, or other signs of hematologic abnormalities. Common conditions that warrant testing include sickle cell anemia (HbSS), sickle cell trait (HbAS), beta-thalassemia, hemoglobin C disease, and hemoglobin E disorders. In regions with high prevalence of hemoglobinopathies, routine screening is essential to identify carriers and affected infants early, reducing the risk of severe complications such as splenic sequestration or pneumococcal infections.
Neonatal hemoglobin electrophoresis Test Procedure
The Neonatal hemoglobin electrophoresis Test is a simple blood test that can be performed in a laboratory. Before the test, the patient may be asked to avoid certain medications that may affect the results. During the test, our healthcare professional will use a needle to draw blood from a vein in the patient’s arm. The blood sample will then be sent to our laboratory for analysis.
Interpreting Neonatal hemoglobin electrophoresis Test Results
The procedure involves collecting a small blood sample from the newborn, typically via a heel prick within 24 to 48 hours after birth. The sample is placed on a filter paper or gel medium and subjected to an electric current, which separates hemoglobin types based on their charge and migration speed. The resulting band patterns are then compared to reference standards to determine the presence and proportion of normal and abnormal hemoglobins. No fasting or special preparation is required, and the process is safe and minimally invasive.
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FAQs Around Neonatal Hemoglobin Electrophoresis Test
How much does Neonatal hemoglobin electrophoresis Test cost?
The Neonatal hemoglobin electrophoresis Test cost is Rs.750, although it is now available for Rs.729 because of the offer.