Mpo - anca ( p - anca ) Test and its Function
The Mpo-ANCA (p-ANCA) test is a specialized blood test used to detect the presence of anti-neutrophil cytoplasmic antibodies (ANCAs), specifically those targeting myeloperoxidase (MPO), an enzyme found in white blood cells. These antibodies are often associated with autoimmune disorders that cause inflammation in blood vessels, a condition known as vasculitis. By identifying MPO-specific ANCAs, this test helps clinicians diagnose and monitor diseases such as microscopic polyangiitis and other forms of ANCA-associated vasculitis. It plays a crucial role in differentiating between various autoimmune conditions and guiding appropriate treatment strategies.
Conditions that may require Mpo - anca ( p - anca ) Test
Doctors may recommend the Mpo-ANCA (p-ANCA) test when a patient presents symptoms suggestive of autoimmune vasculitis or related inflammatory disorders. Common indications include persistent fever, unexplained weight loss, fatigue, joint pain, skin rashes, and organ dysfunction—particularly involving the kidneys or lungs. It is also used to evaluate conditions like ulcerative colitis, Churg-Strauss syndrome, and primary sclerosing cholangitis. The test is valuable in both initial diagnosis and ongoing monitoring of disease activity or treatment response.
Mpo - anca ( p - anca ) Test Procedure
The procedure for the Mpo-ANCA (p-ANCA) test is straightforward and minimally invasive. A trained technician collects a blood sample from a vein, typically in the arm. No fasting is required prior to the test, and it is suitable for individuals across all age groups. Once collected, the sample is analyzed in a laboratory to detect the presence and concentration of MPO-specific antibodies. Results are usually available within 24 to 48 hours, and home collection services are often offered for added convenience.
Interpreting Mpo - anca ( p - anca ) Test Results
Test results are interpreted based on the presence and levels of MPO antibodies in the blood. A positive result may indicate an autoimmune condition such as microscopic polyangiitis or another form of vasculitis. However, results must be considered alongside clinical symptoms and other diagnostic findings, as false positives can occur. A negative result does not entirely rule out disease but may suggest a different underlying cause. Physicians use these insights to confirm diagnoses, assess disease severity, and tailor treatment plans accordingly.
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FAQs Around Mpo - anca ( p - anca ) Test
How much does Mpo - anca ( p - anca ) Test cost?
The Mpo – anca ( p – anca ) Test cost is Rs.770, although it is now available for Rs.741 because of the offer.
